Maladie de kaposi developpee sur greffon de peau chez un patient infecte par le VIH a Abidjan

Introduction : La maladie de Kaposi est une proliferation maligne multifocale de cellules endotheliales. 95 des cas observes a Abidjan; sont associes au SIDA. Observation : Nous rapportons chez un malade atteint de SIDA un cas d' erysipele de jambe complique de fasciite necrosante; sur laquelle se sont developpees des lesions de maladie de Kaposi a la phase de cicatrisation. Conclusion Devant une lesion angiomateuse chez un malade seropositif presentant une grosse jambe; il faudrait evoquer une maladie de Kaposi

Bacterial Isolates from Necrotizing Fasciitis : a Clinico-Pathological Perspective

Background : Necrotizing fasciitis (NF) is a progressive; polymicrobial; potentially fatal soft tissue infection that can affect both sexes; all age groups and any anatomical region of the body. Identification of the offending microorganisms is important; since the eventual outcomeof treatment is dependent on aggressive; chemotherapeutic and supportive therapy. Aim : To determine the spectrum of aerobic bacterialorganisms responsible for NF in Sokoto; Northwestern Nigeria; and to establish a baseline for which further studies can be conduct Patients and Methods : A 5-year prospective study of aerobic bacteria isolated from all consecutive patients with NF seen at the Usmanu Danfodiyo University Teaching Hospital; Sokoto; Nigeria from January 2001 to December 2005. All necessary information from each patient was fed into the computer for analysis. Results: There were 62 patients; of which 33 (53.2) were males while the remaining 29 (46.8) were females. The ages ranged from six days to 70 years (mean = 21.4 years). One or more precipitating factors were identified in) patients; while 40 (64.5) patients had identifiable pre-morbid pathology. The body surface area (BSA) involved ranged from 1 3 32 (51.6). The commonest anatomical region involved was the trunk in 23 (37.1) patients; this was followed by the lower limbs; upper limbs; head and neck; perineum and buttocks in that order. From the 62 patients; 176 aerobic cultures were carried out. Of this; 147 cultures (83.5) were positive; while the remaining 29 (16.5) grew no organisms after 48 hours of incubation. The commonest offending organisms were Staphylococcus aureus and Pseudomonas aeruginosa. Infection was polymicrobial in; 64 of patients. Cephalosporins; quinolones and aminoglycosides were the most sensitive antibiotics. Multiple wound debridements were required in nearly half of the patients. The duration of hospital stay ranged from 3 132 days (mean = 39 days). The overall mortality was 14.5. Conclusion : NF is essentially polymicrobial; deriving significant contributions from both gram-negative and gram-positive bacteria. The cultural characteristics of the disease; and sensitivity to antibiotics; require periodic assessments

Pseudosarcoma in marfan's syndrome : a case study

Pseudosarcomatous fasciitis was reported by Knowaler et al in 1955. It is a benign and quasi-neoplastic proliferation of fibroblasts; which is often mistaken for a sarcoma because of its rapid growth; rich cellularity and mitotic activity. It is one of the more common soft tissue lesions and exceeds in frequency other tumor or tumor-like lesions of fibrous tissue. This attested to by the more than 1000 cases that were reviewed at the American Armed Forces Institute of Pathology (AFIP) in a 20 year period. The case of pseudosarcoma occuring in a patient with marfan's syndrome in Seychelles is reported